The light works: non-invasive optical 3D imaging of microstructure and microcirculation within tissue beds in vivo
Advances in optical technologies have spurred many new applications of light in biology and medicine. The expanding fields of optical diagnostics and therapeutics include such diverse topics as photodynamic therapy for cancers and other diseases, fluorescence endoscopy for early tumor detection, photoacoustic imaging for deep tissue vascular visualization, and optical coherence tomography (OCT) for superficial tissue assessment. OCT is a new medical imaging modality in which the coherent interference of a wide spectrum light source is used to create a high resolution (micron-scale) subsurface image of tissue microstructure. Recently, we have supplemented the microstructural OCT images with additional contrast mechanisms such as blood flow imaging using the static and dynamic (Doppler) speckle effects, which provide us the ability to perform label-free optical microangiography (OMAG) of microcirculatory tissue beds. The ability to visualize tissue blood flow at the microcirculation level is important in a variety of biomedical applications, some of which (along with the OCT basics and the enabling technologies) will be highlighted in this talk. Examples using OMAG to delineate the dynamic blood perfusion, down to capillary level resolution, within living tissues will be given, including cerebral blood flow in small animals and retinal blood flow in humans.
Ruikang (Ricky) Wang, PhD (Glasgow, ’95), is currently a Professor of Bioengineering and Professor of Ophthalmology with the University of Washington, Seattle, USA. After two years’ postdoctoral research training at Glasgow, Scotland, he joined as a Lecturer, and then, Senior Lecturer in Bioimaging Science with Keele Medical School, England. In 2002, he became a Chair Professor in Biomedical Optics with Cranfield University, England, where he created and directed Biophotonics and Imaging Laboratory. In 2005, he joined Oregon Health and Science University, Oregon, where he was a Professor of Biomedical Engineering and Anesthesiology and the Director of Biophotonics and Imaging Laboratory. In 2010, he moved to scenic and vibrant Seattle in Washington. Dr Wang is a leading figure in biophotonics and optical coherence tomography worldwide. He is author of more than 200 peer-reviewed journal articles (with a current H-index = 35), one monograph in optical information processing, as well as 12 book chapters. He is a fellow of Optical Society of America (OSA), a fellow of International Society for Optics and Photonics (SPIE) and a chartered member of the Biomedical Imaging and Technology Study Section for National Institutes of Health (NIH), USA. He currently serves as an associate editor for a number of leading international journals in biomedical optics, including Journal of Biomedical Optics and Biomedical Optics Express. His current research interests include biophotonics and imaging, optical coherence tomography, optical microangiography, photoacoustic imaging and their applications in neurology, ophthalmology, dermatology and cancer.
2012年10月24日(星期三) 上午 9:00
主要从事量子光学与量子信息、低维固态量子系统等的理论与实验研究。代表性成果包括：实验制备出八光子纠缠态并完成八方量子通讯复杂度实验，成果入选2011年度中国十大科技新闻；实现量子的惠勒延迟选择实验，制备出了光的波-粒量子叠加状态，丰富了人们对玻尔互补原理的理解，成果以封面故事文章的形式发表在Nature Photonics上。已发表SCI论文90余篇，其中以第一作者或通讯作者发表Nature Photonics 1篇，Nature Physics 2篇，Nature Communications 2篇，Physical Review Letters 4篇。研究成果多次被Physics world, Science news, Nature Photonics, Nature Physics, Nature CHINA, 2physics等国际著名科学媒体与杂志作为重要进展重点评论。
Multi-contrast photoacoustic microscopy: listening to anatomy, function, metabolism, and biomarkers in vivo
Photoacoustic microscopy (PAM), combining focused optical excitation and ultrasonic detection, enables in vivo multi-contrast characterization of biological tissues down to the cellular level. In PAM, light absorption by endogenous biomolecules or exogenous biomarkers thermoelastically induces a local pressure rise and launches an ultrasonic wave, which propagates through the tissue and is received by an acoustic detector to form an image. This talk will focus on anatomical, functional, metabolic, and molecular PAM at various in vivo sites, including the brain, skin, and eye. The broad applications of PAM in neurology, vascular biology, oncology, and dermatology will be highlighted.
Dr. Hu is currently a postdoctoral research associate in the Optical Imaging Laboratory at Washington University in St. Louis, and will be joining the Department of Biomedical Engineering at the University of Virginia as an assistant professor in May, 2013. He received his B.S. and M.S. degrees in Electronic Engineering at Tsinghua University in 2002 and 2005, respectively, and earned his Ph.D. degree in Biomedical Engineering at Washington University in St. Louis. His research interest is to combine optics and ultrasound for in vivo anatomical, functional, metabolic, and molecular imaging at multiple spatial and temporal scales. His current research focuses on the technical development of photoacoustic microscopy for in vivo multi-contrast analysis of physiology and pathophysiology at the microscopic level.
报告人：Prof. Edward Kai-Ning Yung, City University of Hong Kong
报告题目：Wave Penetration into a Human Head, a Bi-anisotropic Body of Arbitrary Shape
It is postulated that brain tissue is bi-anisotropic in nature, similar to snails and other soft-tissue animals. The dielectric constant and other electromagnetic characteristics of many biological tissues measured by conventional methods are therefore excessively high. Moreover, reliable theoretical analyses of wave penetration into a human head are not found in literature.
The talk will begin with a brief introduction of bi-anisotropy, historical discoveries, and recent developments. It is followed by a review on electromagnetic bi-anisotropy, types of bi-anisotropic media, characteristics of wave propagations in a bi-anisotropic medium, and attempts in making composite bi-anisotropic materials.
Conventional methods used in analyzing wave scattered from a bi-anisotropic body of a given shape will be revisited. Errors in the existing methods will be rectified. With the ever increasing popularity of mobile communications, wave penetration into a human head due to an antenna in proximity will be highlighted. It is a one-size-fits-all method for analyzing an antenna loaded with any material, from the simple lossless dielectric cube to the lossy bi-anisotropic one of arbitrary shape. It is easy-to-use because there is no need to derive the configuration-dependent dyadic Green’s functions. Moreover, an efficient method has been developed to solve the integro-differential equations. By choosing a dipole radiating in the vicinity of a lossless dielectric sphere as a reference, validity of the present computational method is demonstrated by comparing our results with those derived from rigorous analytical methods. The method is then used to study an antenna loaded with bi-anisotropic materials and the results obtained are very encouraging. The talk will be concluded by flashing ideas in mass producing bi-anisotropic materials cost-effectively and the potential uses of the present studies.
Edward Kai-Ning YUNG was born in Hong Kong. He went to the United States of America in 1969 and studied in the University of Mississippi, a state university renowned for excellence in applied electromagnetics. After getting a Bachelor of Science degree in Electrical Engineering with Special Distinction in 1972, he stayed with his alma mater, and eventually earned his master and doctoral degrees in 1974 and 1977, receptively. Then, he worked in the University of Illinois at Urbana-Champaign as a Research Associate before returning to Hong Kong in 1978, just in time to play a role in the six-fold expansion of university education in Hong Kong the last three decades.
He joined the newly established City Polytechnic of Hong Kong in 1984 for setting up a new department. He headed the Department of Electronic Engineering again in 1995. In a maximum two terms of six years, he converted it into a strong one with over 60 professors, including many world-renowned scholars. Since then, City University was consistently highly rated by international bodies. For example, it was ranked 18 in H-index and in citation in electrical and electronic engineering in the world by Microsoft in 2012.
For his contributions, he was installed as one of the first four professors in the polytechnic in 1988. After the polytechnic was granted a university status, Prof. Yung was awarded one of the first two personal chairs in 1994.
Edward is always active in research in computational electromagnetics, antenna design, and microwave devices. He founded the Wireless Communications Research Centre in 1994. Over the years, he has built a strong team in the design of components, devices, software, and system integration for wireless and RFID systems. On the theoretical side, he has done pioneering work in the analysis of ferrite and bi-anisotropic materials. He is the principal investigator of tens of projects amounting to HK$100 million. He has authored/co-authored 270 papers in top-notch journals. He and his students have presented equally many articles in international conferences where he has awarded many prizes for outstanding papers.
Prof. Yung is active in consultancy and technology transfers. He holds six patents. For his contributions in applied research, he was awarded many prizes and commendations. He was named Who’s Who in the World in 1997 and Who’s Who in Science and Technology in 1998. He was honored as an honorary professor in five universityies. He was elected to fellowship grade in practically all relevant professional societies, including IEEE in USA, CIE in China, IEE in UK, HKIE and HKAAST in Hong Kong. He is a member of the Academy of Electomagnetics in USA.
Phase Correlation Image Analysis System Subpixel disparity estimation for high quality 3D data generation and precise image co-registration
With years’ continuous research effort on algorithm design and software development, Dr Liu’s group has developed a high performance Phase Correlation Image Analysis System (PCIAS). Equipped with an Enhanced Robust Phase Correlation (ERPC) engine, the newest version of the software package, PCIAS-2012, is capable of measuring image frame shift, rotation (any angles) and scale changes (up to 2 times) and estimate pixel-wise local disparity at about 1/50th pixel accuracy at high processing speed.
The research is supported by SEAS DTC UK, aiming to both civil and military applications, such as precise image co-registration, DEM generation, motion detection and super resolution reconstruction (SRR). In particular, the technology enables 3D data generation from very narrow baseline stereo images to produce low occlusion high accuracy DEMs for urban areas. The capability of the PCIAS-2012 for coping with versatile baseline image stereo matching makes it a powerful tool for measuring topographic change and terrain deformation resulted from geohazards (e.g. earthquake, landslide and mudflow).
刘建国博士领导的研究组创新开发了具有世界先进水平的亚像元图像特征匹配分析技术（PCIAS：Phase Correlation Image Analysis System）。该项基于图像傅里叶变换后辐角相关概念的新技术可以精确量测小于1/50像元的图像影纹错动，已被用于图像精确配准，图像像元点-点配准，运动检测，超级分辨率图像再生。特别重要的是该项技术可以从超窄基线距立体像对产生无遮蔽高精度数字高程模型数据，因此在城市数字高程，地质灾害再造地形，地物体积变化，和多时相变化的定量识别以及强地震所造成的地体三维变形等多方面应用有着广阔的前景和独到的优势。
Reader in Remote Sensing in the Department of Earth Science and Engineering, Imperial College London. M.Sc. 1982 in remote sensing and geology from China University of Geosciences, Beijing, China; Ph.D. 1991 in remote sensing and digital image processing from Imperial College London, UK. Current research activities: sub-pixel technology such as phase correlation feature matching for precise image registration, DEM generation and change detection, InSAR, and GIS multi-data modelling for geohazard and neotectonics studies. Developed several novel and popular image processing techniques such as BCET (Balance Contrast Enhancement Technique), DDS (Direct Decorrelation Stretch), Simulated Reflectance and SFIM (Smoothing Filter based Intensity Modulation, cited more than 250 times). Teaching activities: undergraduate and M.Sc. remote sensing and image processing courses, and Ph.D. supervision. He won the Jerald J. Cook Memorial Award at the 9th ERIM Thematic Conferences 1993 and IGARSS’99 Best Paper Prize in 1999, and Major Award of Royal Academy of Engineering for UK-China exchange research.
报告题目：Computational wave-field engineering: imaging and controlling
Recent developments in semiconductor and information technology enable communications between optics and computers, which is revolutionizing optical wave-fronts imaging and controlling. For example, the next generation of cameras will integrate the computer as part of the imaging system itself, with algorithms replacing optical elements such as lenses and filters. The first part of this talk will describe powerful computational techniques for phase-space optics and phase imaging. Phase imaging retrieves 2D phase map of diffractive/scattering fields, while phase-space measurements recover 4D coherence properties of the fields. The second part will describe methods of synthesizing arbitrary 2D spectral and 4D coherence properties of wave-fields. Measurements and controlling of wave-field will allow new applications in imaging, signal processing, and nonlinear dynamics.
司徒国海，是普林斯顿大学电子工程系的博士后助理研究员，他于2001年在南开大学获学士学位；2006年在中国科学院研究生院获博士学位。在来普林斯顿之前他曾先后在爱尔兰IRCSET基金、德国洪堡基金的资助下分别在都柏林大学电机工程系和斯图加特大学（University of Stuttgart）技术光学研究所从事研究工作。司徒国海对计算光学成像、相位恢复、数字全息、相空间光学、光学图像处理等领域均有研究，取得一些成果受到同行重视，曾在美国光学学会举办的若干学术会议上作特邀报告，或担任技术程序委员会委员。他发表的22篇SCI论文已被引用500余次，其中有一篇被引150余次，一篇90余次。此外，他的部分研究成果已被写入多本国外出版的学术著作。他是Optics Letters、Optics Express、IEEE Transactions on Image Processing等期刊的审稿人。
1）Coordinated Beamforming for Multiuser MISO Interference Channel under Rate Outage Constraints
2） Convex Analysis Based Non-negative Blind
Source Separation and its Applications
Chong-Yung Chi (祁忠勇)
Chong-Yung Chi (祁忠勇) received the Ph.D. degree in Electrical Engineering from the University of Southern California, Los Angeles, California, in 1983. From 1983 to 1988, he was with the Jet Propulsion Laboratory, Pasadena, California. He has been a Professor with the Department of Electrical Engineering since 1989 and the Institute of Communications Engineering (ICE) since 1999 (also the Chairman of ICE during 2002-2005), National Tsing Hua University, Hsinchu, Taiwan. He has published more than 180 technical papers, including more than 60 journal papers (mostly in IEEE Trans. Signal Processing), 2 book chapters and more than 110 peer-reviewed conference papers, as well as a graduate-level textbook, Blind Equalization and System Identification, Springer-Verlag, 2006. His current research interests include signal processing for wireless communications, convex analysis and optimization for blind source separation, biomedical and hyperspectral image analysis.
Dr. Chi is a senior member of IEEE. He has been a Technical Program Committee member for many IEEE sponsored and co-sponsored workshops, symposiums and conferences on signal processing and wireless communications, including Co-organizer and General Co-chairman of 2001 IEEE Workshop on Signal Processing Advances in Wireless Communications (SPAWC), and Co-Chair of Signal Processing for Communications (SPC) Symposium, ChinaCOM 2008 & Lead Co-Chair of SPC Symposium, ChinaCOM 2009. He was an Associate Editor (AE) of IEEE Trans. Signal Processing (5/2001~4/2006), IEEE Trans. Circuits and Systems II (1/2006-12/2007), IEEE Trans. Circuits and Systems I (1/2008-12/2009), AE of IEEE Signal Processing Letters (6/2006~5/2010), and a member of Editorial Board of EURASIP Signal Processing Journal (6/2005~5/2008), and an editor (7/2003~12/2005) as well as a Guest Editor (2006) of EURASIP Journal on Applied Signal Processing. He was a member of IEEE Signal Processing Committee on Signal Processing Theory and Methods (2005-2010). Currently, he is a member of IEEE Signal Processing Committee on Signal Processing for Communications and Networking, and an AE of IEEE Trans. Signal Processing.
Sumriddetchkajorn博士1999年获得OSA 的“New Focus Student Award”，2000年获得SPIE最高奖“D.J.Lovell Award”，IEEE-LEOS研究生奖学金，他是唯一获得此三个光学学会组织学生奖学金的学生。泰国国王陛下赞助下的科学和技术推广基金会2003年授予他青年技师奖，2004年授予Sumriddetchkajorn博士青年科学家奖。 2005年，Sumriddetchkajorn博士被国际光学委员会和阿卜杜勒·萨拉姆国际理论物理中心授予ICO/ICTP奖，他是唯一获得此奖项的学者。Sumriddetchkajorn博士现在是国际光学工程学会（SPIE），美国光学学会（OSA），（电气与电子工程学会）IEEE高级会员。
Part One: Data-non-intrusive photonics-based credit card verifiers
Abstract: This talk will highlight our proposed hyperspectral imaging-based optical structure for verifying a credit card without invading privacy data of the credit card’s owner. Our key idea comes from the fact that the fine detail of the embossed hologram stamped on the credit card is hard to duplicate and therefore its key color features can be used for distinguishing between the real and counterfeit ones. By using a feed-forward neural network, our proposed system can effectively separate genuine and counterfeit credit cards with a false rejection rate (FRR) of 5.26%. Key features include low cost, simplicity, no moving part, no need of an additional decoding key, and adaptive learning.
Part Two: Diffusing optics and photonics in our community
Abstract: This talk will focus on activities in our “Shining-Spectrum-to-Society” project where we aim to raise the public awareness of science and technology in optics and photonics. We combine hands-on, media engineering, social networking, inquiry, and problem –based approaches to nurture and reinforce the scientific thinking method to students, teachers and general publics. Available media related to basic optics and applications in everyday life are used to get their attentions as well as to encourage students to do their science or engineering projects. In addition, we have developed an educational “Learning by Playing with Photonics” kit comprising of 20 elements that can be used to demonstrate more than 17 topics.